session overview
- Integrative Methods
- Transcriptome-Wide Association Studies (TWAS)
- Resources
- Other “-WAS” Approaches
- Example Applications in Practice
- Mendelian Randomization
- Basic theory of Mendelian randomization
- Robust methods for Mendelian randomization analysis
- Software and resources
Suggested Readings
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Mai, J., Lu, M., Gao, Q. et al. Transcriptome-wide association studies: recent advances in methods, applications and available databases. Commun Biol 6, 899 (2023). [https://doi.org/10.1038/s42003-023-05279-y]
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Wainberg, M., Sinnott-Armstrong, N., Mancuso, N. et al. Opportunities and challenges for transcriptome-wide association studies. Nat Genet 51, 592–599 (2019). [https://doi.org/10.1038/s41588-019-0385-z]
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Sanderson, E., Glymour, M. M., Holmes, M. V., Kang, H., Morrison, J., Munafò, M. R., Palmer, T., Schooling, C. M., Wallace, C., Zhao, Q., & Davey Smith, G. (2022). Mendelian randomization. Nature Reviews Methods Primers, 2(1), 1–21. https://doi.org/10.1038/s43586-021-00092-5