Session 9: Functional genomics

session overview

  • A framework of functional genomics approaches for GWAS follow-up
  • Cell type and context-specific function of cancer-associated variants and genes
  • Identifying and characterizing “missing” variants and genes underlying GWAS loci

Suggested Readings

  • Gaulton, K. J., Preissl, S., & Ren, B. (2023). Interpreting non-coding disease-associated human variants using single-cell epigenomics. Nature Reviews. Genetics, 24(8), 516–534. https://doi.org/10.1038/s41576-023-00598-6
  • Cuomo, A. S. E., Nathan, A., Raychaudhuri, S., MacArthur, D. G., & Powell, J. E. (2023). Single-cell genomics meets human genetics. Nature Reviews. Genetics, 1–15. https://doi.org/10.1038/s41576-023-00599-5