Session 3: Fine-mapping and colocalization

Supplemental

Several different fine mapping software are used commonly for post-GWAS analysis. There is no universal “best” method. Most suitable method usually depends on different factors including causal scenarios, underlying statistical model/method, computational feasibility and others. Here is a (partially complete) list of software that have been used in post GWAS in silico analyses.

Additional Fine-mapping software:

You can visit the vignette pages for each of these to learn and understand more about the intuition of the methods and find the suitable application for your analysis.

Additional colocalization software:

  • HyPrColoc: Link : Colocalization with more than 2 traits/outcomes to choose the best subset of colocalizing outcomes.